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ampC cephalosporinase of Escherichia coli K-12 has a different evolutionary origin from that of beta-lactamases of the penicillinase type.

A 1536-nucleotide-long sequence that carries the ampC beta-lactamase gene of the Escherichia coli K-12 chromosome has been determined. This gene codes for a protein of 377 amino acids, of which the first 19 amino acids form a signal peptide. The molecular weight of the mature enzyme was determined t...

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Bibliographic Details
Main Authors: Jaurin, B, Grundström, T
Format: Artigo
Language:Inglês
Published: 1981
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC320287/
https://ncbi.nlm.nih.gov/pubmed/6795623
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