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Computational approaches to selecting and optimising targets for structural biology

Selection of protein targets for study is central to structural biology and may be influenced by numerous factors. A key aim is to maximise returns for effort invested by identifying proteins with the balance of biophysical properties that are conducive to success at all stages (e.g. solubility, cry...

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Autors principals: Overton, Ian M., Barton, Geoffrey J.
Format: Artigo
Idioma:Inglês
Publicat: Academic Press 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3202631/
https://ncbi.nlm.nih.gov/pubmed/21906678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2011.08.014
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