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c-Kit-Mediated Functional Positioning of Stem Cells to Their Niches Is Essential for Maintenance and Regeneration of Adult Hematopoiesis

The mechanism by which hematopoietic stem and progenitor cells (HSPCs) through interaction with their niches maintain and reconstitute adult hematopoietic cells is unknown. To functionally and genetically track localization of HSPCs with their niches, we employed novel mutant loxPs, lox66 and lox71...

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Библиографические подробности
Главные авторы: Kimura, Yuki, Ding, Bisen, Imai, Norikazu, Nolan, Daniel J., Butler, Jason M., Rafii, Shahin
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3202594/
https://ncbi.nlm.nih.gov/pubmed/22046410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026918
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