Species-Specific Codon Context Rules Unveil Non-Neutrality Effects of Synonymous Mutations

BACKGROUND: Codon pair usage (codon context) is a species specific gene primary structure feature whose evolutionary and functional roles are poorly understood. The data available show that codon-context has direct impact on both translation accuracy and efficiency, but one does not yet understand h...

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Main Authors: Moura, Gabriela R., Pinheiro, Miguel, Freitas, Adelaide, Oliveira, José L., Frommlet, Jörg C., Carreto, Laura, Soares, Ana R., Bezerra, Ana R., Santos, Manuel A. S.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3202573/
https://ncbi.nlm.nih.gov/pubmed/22046369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026817
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