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Efficient Generation of Fully Reprogrammed Human iPS Cells via Polycistronic Retroviral Vector and a New Cocktail of Chemical Compounds

Direct reprogramming of human somatic cells into induced pluripotent stem (iPS) cells by defined transcription factors (TFs) provides great potential for regenerative medicine and biomedical research. This procedure has many challenges, including low reprogramming efficiency, many partially reprogra...

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Detalhes bibliográficos
Main Authors: Zhang, Zhonghui, Gao, Yongxing, Gordon, Albert, Wang, Zack Z., Qian, Zhijian, Wu, Wen-Shu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3202534/
https://ncbi.nlm.nih.gov/pubmed/22046312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026592
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