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Impact of Genetic Variation in SORCS1 on Memory Retention
OBJECTIVE: We previously reported that genetic variants in SORCS1 increase the risk of AD, that over-expression of SorCS1 reduces γ-secretase activity and Aβ levels, and that SorCS1 suppression increases γ-secretase processing of APP and Aβ levels. We now explored the effect of variation in SORCS1 o...
Sparad:
| Huvudupphovsmän: | , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Public Library of Science
2011
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3202519/ https://ncbi.nlm.nih.gov/pubmed/22046233 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024588 |
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