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Extracellular Hsp90 serves as a co-factor for MAPK activation and latent viral gene expression during de novo infection by KSHV

The Kaposi’s sarcoma-associated herpesvirus (KSHV) is the causative agent of Kaposi’s sarcoma (KS), an important cause of morbidity and mortality in immunocompromised patients. KSHV interaction with the cell membrane triggers activation of specific intracellular signal transduction pathways to facil...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Qin, Zhiqiang, DeFee, Michael, Isaacs, Jennifer, Parsons, Chris
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3202419/
https://ncbi.nlm.nih.gov/pubmed/20451233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2010.03.052
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