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Synthesis and conformational studies of ribooligonucleotides which contain an alternating C-G sequence and show unusual circular dichroism spectra.

The poly [r(C-G)] duplex shows an unusually large negative CD band in the long wavelength region. In order to elucidate this phenomenon, r(C-G-C-G) and r(C-G-C-G-C-G) were synthesized by a phosphotriester method and their properties were examined by UV, CD, 1H and 31P NMR spectroscopy. These ribooli...

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Библиографические подробности
Опубликовано в: :Nucleic Acids Res
Главные авторы: Uesugi, S, Ohkubo, M, Ohtsuka, E, Ikehara, M, Kobayashi, Y, Kyogoku, Y
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 1984
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC320201/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6493981/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/12.20.7793
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