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Monoamine oxidase A inhibitor occupancy during treatment of major depressive episodes with moclobemide or St. John’s wort: an [(11)C]-harmine PET study

BACKGROUND: Monoamine oxidase A (MAO-A) inhibitor antidepressants raise levels of multiple monoamines, whereas the selective serotonin reuptake inhibitors (SSRIs) only raise extracellular serotonin. Despite this advantage of MAO-A inhibitors, there is much less frequent development of MAO inhibitors...

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Detalhes bibliográficos
Main Authors: Sacher, Julia, Houle, Sylvain, Parkes, Jun, Rusjan, Pablo, Sagrati, Sandra, Wilson, Alan A., Meyer, Jeffrey H.
Formato: Artigo
Idioma:Inglês
Publicado em: Canadian Medical Association 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3201991/
https://ncbi.nlm.nih.gov/pubmed/21463543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1503/jpn.100117
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