Gut Homing Receptors on CD8 T Cells Are Retinoic Acid Dependent and Not Maintained by Liver Dendritic or Stellate Cells

BACKGROUND & AIMS: Lymphocytes primed by intestinal dendritic cells (DC) express the gut-homing receptors CCR9 and α4β7, which recognize CCL25 and mucosal addressin cell-adhesion molecule-1 in the intestine promoting the development of regional immunity. In mice, imprinting of CCR9 and α4β7 is d...

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Autori principali: Eksteen, Bertus, Mora, J. Rodrigo, Haughton, Emma L., Henderson, Neil C., Lee–Turner, Laura, Villablanca, Eduardo J., Curbishley, Stuart M., Aspinall, Alex I., Von Andrian, Ulrich H., Adams, David H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3201985/
https://ncbi.nlm.nih.gov/pubmed/19233184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2009.02.046
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