Tissue-Restricted Expression of Nrf2 and Its Target Genes in Zebrafish with Gene-Specific Variations in the Induction Profiles

The Keap1-Nrf2 system serves as a defense mechanism against oxidative stress and electrophilic toxicants by inducing more than one hundred cytoprotective proteins, including antioxidants and phase 2 detoxifying enzymes. Since induction profiles of Nrf2 target genes have been studied exclusively in c...

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Bibliographische Detailangaben
Hauptverfasser: Nakajima, Hitomi, Nakajima-Takagi, Yaeko, Tsujita, Tadayuki, Akiyama, Shin-Ichi, Wakasa, Takeshi, Mukaigasa, Katsuki, Kaneko, Hiroshi, Tamaru, Yutaka, Yamamoto, Masayuki, Kobayashi, Makoto
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3201981/
https://ncbi.nlm.nih.gov/pubmed/22046393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026884
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