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Hepatitis B Virus Impairs TLR9 Expression and Function in Plasmacytoid Dendritic Cells
Plasmacytoid dendritic cells (pDCs) play a key role in detecting pathogens by producing large amounts of type I interferon (IFN) by sensing the presence of viral infections through the Toll-Like Receptor (TLR) pathway. TLR9 is a sensor of viral and bacterial DNA motifs and activates the IRF7 transcr...
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Main Authors: | , , , , , , , , , , |
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Formáid: | Artigo |
Teanga: | Inglês |
Foilsithe: |
Public Library of Science
2011
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Ábhair: | |
Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3201951/ https://ncbi.nlm.nih.gov/pubmed/22046272 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026315 |
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