Hepatitis B Virus Impairs TLR9 Expression and Function in Plasmacytoid Dendritic Cells

Plasmacytoid dendritic cells (pDCs) play a key role in detecting pathogens by producing large amounts of type I interferon (IFN) by sensing the presence of viral infections through the Toll-Like Receptor (TLR) pathway. TLR9 is a sensor of viral and bacterial DNA motifs and activates the IRF7 transcr...

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Autors principals: Vincent, Isabelle E., Zannetti, Claudia, Lucifora, Julie, Norder, Helene, Protzer, Ulrike, Hainaut, Pierre, Zoulim, Fabien, Tommasino, Massimo, Trépo, Christian, Hasan, Uzma, Chemin, Isabelle
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3201951/
https://ncbi.nlm.nih.gov/pubmed/22046272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026315
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