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Methadone adverse reaction presenting with large increase in plasma methadone binding: a case series

INTRODUCTION: The use of methadone as an analgesic is on the increase, but it is widely recognized that the goal of predictable and reproducible dosing is confounded by considerable variability in methadone pharmacokinetics, and unpredictable side effects that include sedation, respiratory depressio...

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Библиографические подробности
Главные авторы: Lu, Wenjie J, Zhou, Weidong, Kreutz, Yvonne, Flockhart, David A
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3201932/
https://ncbi.nlm.nih.gov/pubmed/21985665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-1947-5-513
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