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Monitoring enzyme activity using a diamagnetic chemical exchange saturation transfer MRI contrast agent

Chemical Exchange Saturation Transfer (CEST) is a new approach to generate magnetic resonance imaging (MRI) contrast that allows monitoring of protein properties in vivo. In this method, radiofrequency is used to saturate the magnetization of specific protons on a target molecule, where it is then t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Liu, Guanshu, Liang, Yajie, Bar-Shir, Amnon, Chan, Kannie W.Y., Galpoththawela, Chulani S., Bernard, Segun M., Tse, Terence, Yadav, Nirbhay N, Walczak, Piotr, McMahon, Michael T., Bulte, Jeff W.M., van Zijl, Peter C.M., Gilad, Assaf A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3201833/
https://ncbi.nlm.nih.gov/pubmed/21919523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja204701x
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