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Underwound DNA under Tension: Structure, Elasticity, and Sequence-Dependent Behaviors

DNA melting under torsion plays an important role in a wide variety of cellular processes. In the present Letter, we have investigated DNA melting at the single-molecule level using an angular optical trap. By directly measuring force, extension, torque, and angle of DNA, we determined the structura...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sheinin, Maxim Y., Forth, Scott, Marko, John F., Wang, Michelle D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3201814/
https://ncbi.nlm.nih.gov/pubmed/21981534
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