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Human natural regulatory T cell development, suppressive function and post-thymic maturation in a humanized mouse model
CD4+ regulatory T (Treg) cells control adaptive immune responses and promote self-tolerance. Various humanized mouse models have been developed in efforts to reproduce and study a human immune system. However, in models that require T cell differentiation in the recipient murine thymus, only low num...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3201793/ https://ncbi.nlm.nih.gov/pubmed/21876039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100394 |
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