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Common Colorectal Cancer Risk Variants in SMAD7 are Associated with Survival Among Pre-Diagnostic Non-Steroidal Anti-Inflammatory Drug Users: a Population-Based Study of Post-Menopausal Women
Common single nucleotide polymorphisms (SNPs) in SMAD7 (18q21) have been linked to colorectal cancer (CRC) risk in genome-wide association studies, but little is known about their effects on survival. SMAD7 regulates gastrointestinal inflammation by inhibiting transforming growth factor-β (TGFB), wh...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3201720/ https://ncbi.nlm.nih.gov/pubmed/21910156 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gcc.20913 |
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