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The Use of Imputed Values in the Meta-Analysis of Genome-Wide Association Studies

In Genome-wide association studies (GWAS), it is common practice to impute the genotypes of untyped single-nucleotide polymorphism by exploiting the linkage disequilibrium structure among SNPs. Use of imputed genotypes improves genome coverage and makes it possible to perform meta-analysis combining...

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Autors principals: Jiao, Shuo, Hsu, Li, Hutter, Carolyn M., Peters, Ulrike
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3201718/
https://ncbi.nlm.nih.gov/pubmed/21769935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.20608
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