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A computational statistics approach for estimating the spatial range of morphogen gradients

A crucial issue in studies of morphogen gradients relates to their range: the distance over which they can act as direct regulators of cell signaling, gene expression and cell differentiation. To address this, we present a straightforward statistical framework that can be used in multiple developmen...

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Hlavní autoři: Kanodia, Jitendra S., Kim, Yoosik, Tomer, Raju, Khan, Zia, Chung, Kwanghun, Storey, John D., Lu, Hang, Keller, Philipp J., Shvartsman, Stanislav Y.
Médium: Artigo
Jazyk:Inglês
Vydáno: Company of Biologists 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3201657/
https://ncbi.nlm.nih.gov/pubmed/22007136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.071571
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