Mitochondrially Targeted α-Tocopheryl Succinate Is Antiangiogenic: Potential Benefit Against Tumor Angiogenesis but Caution Against Wound Healing

AIMS: A plausible strategy to reduce tumor progress is the inhibition of angiogenesis. Therefore, agents that efficiently suppress angiogenesis can be used for tumor suppression. We tested the antiangiogenic potential of a mitochondrially targeted analog of α-tocopheryl succinate (MitoVES), a compou...

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Bibliographische Detailangaben
Hauptverfasser: Rohlena, Jakub, Dong, Lan-Feng, Kluckova, Katarina, Zobalova, Renata, Goodwin, Jacob, Tilly, David, Stursa, Jan, Pecinova, Alena, Philimonenko, Anatoly, Hozak, Pavel, Banerjee, Jaideep, Ledvina, Miroslav, Sen, Chandan K., Houstek, Josef, Coster, Mark J., Neuzil, Jiri
Format: Artigo
Sprache:Inglês
Veröffentlicht: Mary Ann Liebert, Inc. 2011
Schlagworte:
Forum Original Research Communication Mitochondria-Targeted Therapeutics (J. Neuzil and S.J. Ralph, Eds.)
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3201633/
https://ncbi.nlm.nih.gov/pubmed/21902599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2011.4192
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