Proteolytic Cleavage of Versican and Involvement of ADAMTS-1 in VEGF-A/VPF-Induced Pathological Angiogenesis

Malignant tumors and chronic inflammatory diseases induce angiogenesis by overexpressing vascular endothelial growth factor A (VEGF-A/VPF). VEGF-A-induced pathological angiogenesis can be mimicked in immunoincompetent mice with an adenoviral vector expressing VEGF-A(164) (Ad-VEGF-A(164)). The initia...

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Main Authors: Fu, Yineng, Nagy, Janice A., Brown, Lawrence F., Shih, Shou-Ching, Johnson, Pamela Y., Chan, Christina K., Dvorak, Harold F., Wight, Thomas N.
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2011
Fag:
Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3201172/
https://ncbi.nlm.nih.gov/pubmed/21411713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1369/0022155411401748
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