Factors Influencing the Degradation of Archival Formalin-Fixed Paraffin-Embedded Tissue Sections

The loss of antigenicity in archival formalin-fixed paraffin-embedded (FFPE) tissue sections negatively affects both diagnostic histopathology and advanced molecular studies. The mechanisms underlying antigenicity loss in FFPE tissues remain unclear. The authors hypothesize that water is a crucial c...

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Main Authors: Xie, Ran, Chung, Joon-Yong, Ylaya, Kris, Williams, Reginald L., Guerrero, Natalie, Nakatsuka, Nathan, Badie, Cortessia, Hewitt, Stephen M.
格式: Artigo
語言:Inglês
出版: SAGE Publications 2011
主題:
Review
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3201147/
https://ncbi.nlm.nih.gov/pubmed/21411807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1369/0022155411398488
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