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In Vitro Enhanced Sensitivity to Cisplatin in D67Y BRCA1 RING Domain Protein
BRCA1 is a tumor suppressor protein involved in maintaining genomic integrity through multiple functions in DNA damage repair, transcriptional regulation, cell cycle checkpoint, and protein ubiquitination. The BRCA1-BARD1 RING complex has an E3 ubiquitin ligase function that plays essential roles in...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Libertas Academica
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3201098/ https://ncbi.nlm.nih.gov/pubmed/22084573 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4137/BCBCR.S8184 |
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