Analysing GCN4 translational control in yeast by stochastic chemical kinetics modelling and simulation

BACKGROUND: The yeast Saccharomyces cerevisiae responds to amino acid starvation by inducing the transcription factor Gcn4. This is mainly mediated via a translational control mechanism dependent upon the translation initiation eIF2·GTP·Met-tRNA(i)(Met )ternary complex, and the four short upstream o...

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Autors principals: You, Tao, Stansfield, Ian, Romano, M Carmen, Brown, Alistair JP, Coghill, George M
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3201031/
https://ncbi.nlm.nih.gov/pubmed/21851603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-5-131
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