Nanoparticle-based delivery of siDCAMKL-1 increases microRNA-144 and inhibits colorectal cancer tumor growth via a Notch-1 dependent mechanism

BACKGROUND: The development of effective drug delivery systems capable of transporting small interfering RNA (siRNA) has been elusive. We have previously reported that colorectal cancer tumor xenograft growth was arrested following treatment with liposomal preparation of siDCAMKL-1. In this report,...

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Main Authors: Sureban, Sripathi M, May, Randal, Mondalek, Fadee G, Qu, Dongfeng, Ponnurangam, Sivapriya, Pantazis, Panayotis, Anant, Shrikant, Ramanujam, Rama P, Houchen, Courtney W
格式: Artigo
語言:Inglês
出版: BioMed Central 2011
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3200989/
https://ncbi.nlm.nih.gov/pubmed/21929751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-3155-9-40
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