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Isolation and characterization of endonuclease J: a sequence-specific endonuclease cleaving immunoglobulin genes.

An endonuclease activity which cleaves close to the recombination sites of the immunoglobulin JK segments was found in extracts of chicken bursa of Fabricius and characterized after partial purification. The enzyme preparation also cleaved a VK segment at its 3' end. A similar activity was foun...

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Bibliographic Details
Main Authors: Kataoka, T, Kondo, S, Nishi, M, Kodaira, M, Honjo, T
Format: Artigo
Language:Inglês
Published: 1984
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC320052/
https://ncbi.nlm.nih.gov/pubmed/6089106
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