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The effect of the 3',5' thiophosphoryl linkage on the exonuclease activities of T4 polymerase and the Klenow fragment.

The 3'----5' exonuclease activities of T4 DNA polymerase and the Klenow fragment of Polymerase I towards the phosphoryl and thiophosphoryl 3',5' linkage were examined under comparable conditions of idling-turnover, duplex hydrolysis and turnover during polymerization. With the T4 enzyme there is a n...

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Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Gupta, A P, Benkovic, P A, Benkovic, S J
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 1984
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC320039/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6087297/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/12.14.5897
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