Phase I trial of pemetrexed in combination with cetuximab and concurrent radiotherapy in patients with head and neck cancer

Background: We studied the combination of pemetrexed, a multi-targeted antifolate, and cetuximab, an mAb against the epidermal growth factor receptor, with radiotherapy in poor prognosis head and neck cancer. Patients and methods: Patients received pemetrexed on days 1, 22, and 43 on a dose-escalati...

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Detalhes bibliográficos
Main Authors: Argiris, A., Karamouzis, M. V., Smith, R., Kotsakis, A., Gibson, M. K., Lai, S. Y., Kim, S., Branstetter, B. F., Shuai, Y., Romkes, M., Wang, L., Grandis, J. R., Ferris, R. L., Johnson, J. T., Heron, D. E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3200222/
https://ncbi.nlm.nih.gov/pubmed/21363880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mdr002
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