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Phase I trial of pemetrexed in combination with cetuximab and concurrent radiotherapy in patients with head and neck cancer
Background: We studied the combination of pemetrexed, a multi-targeted antifolate, and cetuximab, an mAb against the epidermal growth factor receptor, with radiotherapy in poor prognosis head and neck cancer. Patients and methods: Patients received pemetrexed on days 1, 22, and 43 on a dose-escalati...
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Autori principali: | , , , , , , , , , , , , , , |
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Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
Oxford University Press
2011
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3200222/ https://ncbi.nlm.nih.gov/pubmed/21363880 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mdr002 |
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