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Net uptake of gamma-aminobutyric acid by a high-affinity system of rat brain synaptosomes.

Rat brain synaptosomes isolated on discontinuous Ficoll gradient carry out rapid net uptake of gamma-aminobutyric acid through a high-affinity system (Km = 6.25 microM; Vmax = 1.2 nmol/min per mg of protein). The uptake of the labeled neurotransmitter is dependent on sodium concentration and is abol...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Pastuszko, A, Wilson, D F, Erecińska, M
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1981
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Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319984/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6940139/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.2.1242
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