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Regulation of TGF-β1-Induced Pro-Apoptotic Signaling by Growth Factor Receptors and Extracellular Matrix Receptor Integrins in the Liver

Hepatocellular carcinoma (HCC) often arises from chronically diseased livers. Persistent liver inflammation causes the accumulation of excessive extracellular matrix (ECM) proteins and impairs the liver function, finally leading to the development of HCC. A pleiotropic cytokine, transforming growth...

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Detalhes bibliográficos
Main Authors: Ozaki, Iwata, Hamajima, Hiroshi, Matsuhashi, Sachiko, Mizuta, Toshihiko
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Research Foundation 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199809/
https://ncbi.nlm.nih.gov/pubmed/22028694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2011.00078
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