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Selective killing of human malignant cell lines deficient in methylthioadenosine phosphorylase, a purine metabolic enzyme.

Seven out of 31 (23%) human malignant tumor cell lines had no detectable methylthioadenosine phosphorylase activity (less than 0.001 nmol/min per mg of protein), assayed with 5'-chloroadenosine as substrate. The enzyme-deficient cell lines were derived from five leukemias, one melanoma, and one...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Kamatani, N, Nelson-Rees, W A, Carson, D A
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1981
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC319979/
https://ncbi.nlm.nih.gov/pubmed/6785752
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