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Regulatory role for hepatic low density lipoprotein receptors in vivo in the dog.

Liver membranes from young beagle dogs were found to possess binding sites that resemble the low density lipoprotein (LDL) receptors originally described in cultured human fibroblasts. Treatment of the dogs with colestipol (a bile acid sequestrant) and mevinolin (a cholesterol synthesis inhibitor) p...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Kovanen, P T, Bilheimer, D W, Goldstein, J L, Jaramillo, J J, Brown, M S
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1981
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319974/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6262757/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.2.1194
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