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Selective Inactivation of Glutaredoxin by Sporidesmin and Other Epidithiopiperazinediones

Glutaredoxin (thioltransferase) is a thiol-disulfide oxidoreductase that displays efficient and specific catalysis of protein-SSG deglutathionylation and is thereby implicated in homeostatic regulation of the thiol-disulfide status of cellular proteins. Sporidesmin is an epidithiopiperazine-2,5-dion...

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Autori principali: Srinivasan, Usha, Bala, Aveenash, Jao, Shu-chuan, Starke, David W., Jordan, T. William, Mieyal, John J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199604/
https://ncbi.nlm.nih.gov/pubmed/16846241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi060440o
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