Lung Tumor-associated Osteoblast-derived Bone Morphogenetic Protein-2 Increased Epithelial-to-Mesenchymal Transition of Cancer by Runx2/Snail Signaling Pathway

Bone is a frequent target of lung cancer metastasis and is associated with significant morbidity and a dismal prognosis. Interaction between cancer cells and the bone microenvironment causes a vicious cycle of tumor progression and bone destruction. This study analyzed the soluble factors secreted b...

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Bibliografiske detaljer
Main Authors: Hsu, Ya-Ling, Huang, Ming-Shyan, Yang, Chih-Jen, Hung, Jen-Yu, Wu, Ling-Yu, Kuo, Po-Lin
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199481/
https://ncbi.nlm.nih.gov/pubmed/21885439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.256156
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