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Alterations in polyamine levels induced by phorbol diesters and other agents that promote differentiation in human promyelocytic leukemia cells

Polyamine levels were evaluated in human HL-60 promyelocytic leukemia cells after treatment with inducers of terminal differentiation. Differentiation in these cells was determined by increases in the percentage of morphologically mature cells and in lysozyme activity. Treatment of the HL-60 cells w...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Huberman, Eliezer, Weeks, Charles, Herrmann, Adria, Callaham, Michael, Slaga, Thomas
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1981
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319946/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6940123/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.2.1062
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