Glycodelin-A Protein Interacts with Siglec-6 Protein to Suppress Trophoblast Invasiveness by Down-regulating Extracellular Signal-regulated Kinase (ERK)/c-Jun Signaling Pathway

During placentation, the cytotrophoblast differentiates into the villous cytotrophoblast and the extravillous cytotrophoblast. The latter invades the decidualized endometrium. Glycodelin-A (GdA) is abundantly synthesized by the decidua but not the trophoblast. Previous data indicate that GdA suppres...

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Bibliographische Detailangaben
Hauptverfasser: Lam, Kevin K. W., Chiu, Philip C. N., Lee, Cheuk-Lun, Pang, Ronald T. K., Leung, Carmen O. N., Koistinen, Hannu, Seppala, Markku, Ho, Pak-Chung, Yeung, William S. B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2011
Schlagworte:
Signal Transduction
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199459/
https://ncbi.nlm.nih.gov/pubmed/21880722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.233841
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