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Novel Role for Mediator Complex Subunit Srb5/Med18 in Termination of Transcription

Mediator complex functions at the recruitment as well as the post-recruitment steps of transcription. Here we provide evidence for a novel role of Mediator in termination of transcription. Mediator subunit Srb5/Med18 cross-links to the 5′ and 3′ ends of INO1 and CHA1. In srb5(−) cells, recruitment o...

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Autors principals: Mukundan, Banupriya, Ansari, Athar
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199451/
https://ncbi.nlm.nih.gov/pubmed/21921038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C111.295915
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