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microRNA-34c is a novel target to treat dementias

MicroRNAs are key regulators of transcriptome plasticity and have been implicated with the pathogenesis of brain diseases. Here, we employed massive parallel sequencing and provide, at an unprecedented depth, the complete and quantitative miRNAome of the mouse hippocampus, the prime target of neurod...

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Détails bibliographiques
Auteurs principaux: Zovoilis, Athanasios, Agbemenyah, Hope Y, Agis-Balboa, Roberto C, Stilling, Roman M, Edbauer, Dieter, Rao, Pooja, Farinelli, Laurent, Delalle, Ivana, Schmitt, Andrea, Falkai, Peter, Bahari-Javan, Sanaz, Burkhardt, Susanne, Sananbenesi, Farahnaz, Fischer, Andre
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199394/
https://ncbi.nlm.nih.gov/pubmed/21946562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.327
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