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Evidence for a higher molecular weight precursor of cholesterol side-chain-cleavage cytochrome P-450 and induction of mitochondrial and cytosolic proteins by corticotropin in adult bovine adrenal cells.

Adult bovine adrenal cortical cells in monolayer culture were used to study the induction of cholesterol side-chain-cleavage cytochrome P-450 by corticotropin (ACTH). In the presence of 1 microM ACTH, there was a 4-fold increase in cortisol production by these cells over a 72-hr period and a corresp...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: DuBois, R N, Simpson, E R, Tuckey, J, Lambeth, J D, Waterman, M R
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1981
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319939/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6262752/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.2.1028
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