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Site-specific proteomic analysis of lipoxidation adducts in cardiac mitochondria reveals chemical diversity of 2-alkenal adduction

The modification of proteins by lipid peroxidation products has been linked to numerous diseases and age-related disorders. Here we report on the identification of endogenous protein targets of electrophilic 2-alkenals in cardiac mitochondria. An aldehyde/keto-specific chemical labeling and affinity...

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Detalhes bibliográficos
Main Authors: Chavez, Juan D., Wu, Jianyong, Bisson, William, Maier, Claudia S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199298/
https://ncbi.nlm.nih.gov/pubmed/21513823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jprot.2011.03.031
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