Systems-level dynamic analyses of fate change in murine embryonic stem cells

Molecular regulation of embryonic stem cell (ESC) fate involves a coordinated interaction between epigenetic(1–4), transcriptional(5–10) and translational(11,12) mechanisms. It is unclear how these different molecular regulatory mechanisms interact to regulate changes in stem cell fate. Here we pres...

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Autors principals: Lu, Rong, Markowetz, Florian, Unwin, Richard D., Leek, Jeffrey T., Airoldi, Edoardo M., MacArthur, Ben D., Lachmann, Alexander, Rozov, Roye, Ma’ayan, Avi, Boyer, Laurie A., Troyanskaya, Olga G., Whetton, Anthony D., Lemischka, Ihor R.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199216/
https://ncbi.nlm.nih.gov/pubmed/19924215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08575
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