Enhanced expression of coproporphyrinogen oxidase in malignant brain tumors: CPOX expression and 5-ALA–induced fluorescence

In photodynamic diagnosis, 5-aminolevulinic acid (5-ALA) is widely used for the fluorescence-guided resection of malignant brain tumors, where 5-ALA is converted to protoporphyrin IX, which exhibits strong fluorescence. Little is known, however, about the detailed molecular mechanisms underlying 5-A...

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Detalhes bibliográficos
Main Authors: Takahashi, Kenkichi, Ikeda, Naokado, Nonoguchi, Naosuke, Kajimoto, Yoshinaga, Miyatake, Shin-Ichi, Hagiya, Yuichiro, Ogura, Shun-Ichiro, Nakagawa, Hiroshi, Ishikawa, Toshihisa, Kuroiwa, Toshihiko
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Clinical Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199158/
https://ncbi.nlm.nih.gov/pubmed/21824890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nor116
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