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Gadd45a Functions as a Promoter or Suppressor of Breast Cancer Dependent on the Oncogenic Stress

Gadd45a plays a pivotal role as a stress sensor that modulates cellular responses to various stress stimuli, including oncogenic stress. We reported that the stress sensor Gadd45a gene functions as a tumor suppressor in Ras-driven breast tumorigenesis via increasing JNK-mediated apoptosis and p38-me...

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Detalhes bibliográficos
Main Authors: Tront, Jennifer S., Haung, Yajue, Fornace, Albert A., Hoffman, Barbara, Liebermann, Dan A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199142/
https://ncbi.nlm.nih.gov/pubmed/21098706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-2177
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