CLOCK Genes and Circadian Rhythmicity in Alzheimer Disease

Disturbed circadian rhythms with sleep problems and disrupted diurnal activity are often seen in patients suffering from Alzheimer disease (AD). Both endogenous CLOCK genes and external Zeitgeber are responsible for the maintenance of circadian rhythmicity in humans. Therefore, modifications of the...

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Main Authors: Thome, J., Coogan, A. N., Woods, A. G., Darie, C. C., Häßler, F.
Format: Artigo
Jezik:Inglês
Izdano: SAGE-Hindawi Access to Research 2011
Teme:
Review Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199059/
https://ncbi.nlm.nih.gov/pubmed/22028968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/383091
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