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c-Jun-N-Terminal Kinase Signaling Is Involved in Cyclosporine-Induced Epithelial Phenotypic Changes

Tubular epithelial cells play a central role in the pathogenesis of chronic nephropathies. Previous toxicogenomic studies have demonstrated that cyclosporine- (CsA-) induced epithelial phenotypic changes (EPCs) are reminiscent of an incomplete epithelial to mesenchymal transition (EMT) in a TGF-β-in...

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Detalhes bibliográficos
Main Authors: Pallet, Nicolas, Thervet, Eric, Anglicheau, Dany
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3199056/
https://ncbi.nlm.nih.gov/pubmed/22028950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/348604
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