Mechanism of activation of cyclic nucleotide phosphodiesterase: requirement of the binding of four Ca2+ to calmodulin for activation.

Kinetic studies on the activation of cyclic nucleotide phosphodiesterase (3',5'-cyclic-nucleotide 5'-nucleotidohydrolase, EC 3.1.4.17) as a function of calmodulin and Ca2+ concentrations have been carried out. A general approach to analyzing the mechanism of activation, which takes into consideratio...

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Julkaisussa:	Proc Natl Acad Sci U S A
Päätekijät:	Huang, C Y, Chau, V, Chock, P B, Wang, J H, Sharma, R K
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	National Academy of Sciences 1981
Aiheet:	Research Article
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319905/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6262778/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.2.871
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