Age-related changes in the default mode network are more advanced in Alzheimer disease

OBJECTIVE: To investigate age-related default mode network (DMN) connectivity in a large cognitively normal elderly cohort and in patients with Alzheimer disease (AD) compared with age-, gender-, and education-matched controls. METHODS: We analyzed task-free–fMRI data with both independent component...

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Détails bibliographiques
Auteurs principaux: Jones, D.T., Machulda, M.M., Vemuri, P., McDade, E.M., Zeng, G., Senjem, M.L., Gunter, J.L., Przybelski, S.A., Avula, R.T., Knopman, D.S., Boeve, B.F., Petersen, R.C., Jack, C.R.
Format: Artigo
Langue:Inglês
Publié: Lippincott Williams & Wilkins 2011
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Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198977/
https://ncbi.nlm.nih.gov/pubmed/21975202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e318233b33d
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