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Covalent modification and repressed transcription of a gene in hepatoma cells.

When liver cells undergo malignant transformation, certain genes cease being expressed. We have studied the structure of one such gene, whose protein product we have designated hepatic protein 22 (hp22), which is not expressed in the two Morris hepatomas studied. We have prepared a chimeric clone of...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Nakhasi, H L, Lynch, K R, Dolan, K P, Unterman, R D, Feigelson, P
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1981
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC319897/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7015332/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.78.2.834
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