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Early and late effects of the DPP-4 inhibitor vildagliptin in a rat model of post-myocardial infarction heart failure

BACKGROUND: Progressive remodeling after myocardial infarction (MI) is a leading cause of morbidity and mortality. Recently, glucagon-like peptide (GLP)-1 was shown to have cardioprotective effects, but treatment with GLP-1 is limited by its short half-life. It is rapidly degraded by the enzyme dipe...

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Hlavní autoři: Yin, Meimei, Silljé, Herman HW, Meissner, Maxi, van Gilst, Wiek H, de Boer, Rudolf A
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3198901/
https://ncbi.nlm.nih.gov/pubmed/21955567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2840-10-85
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